University of Wisconsin–Madison

Category: Diet Exercise Lifestyle

Alcohol and the Brain: One Drink a Day Associated with Brain Shrinkage

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There are many conflicting studies on how alcohol consumption can impact a person’s health, with some studies suggesting light drinking can protect against coronary heart disease and others concluding that drinking can increase your risk for cancer. What does research say about alcohol and the brain? Dr. Remi Daviet joins the podcast to discuss his latest study that found that just one alcoholic drink a day was associated with brain shrinkage, and drinking more could increase that rate exponentially over time.

Guest: Remi Daviet, PhD, assistant professor, Wisconsin School of Business

You Are What You Eat: Study of Diet and Brain Health Shows Cognitive Benefits from Cheese, Wine and Lamb

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A recent study of nearly 1,800 participants from the UK Biobank found that three dietary elements — cheese, wine, and lamb — may improve long-term cognitive outcomes in aging adults. Dr. Auriel Willette, assistant professor of food science and human nutrition at Iowa State University, joins the podcast to discuss these new findings linking diet and cognitive changes. In November 2020, Willette published a study in the Journal of Alzheimer’s Disease titled, “Genetic Factors of Alzheimer’s Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study,” where he and his team studied the effects of particular foods on a person’s brain health over time. As well as the findings surrounding cheese, wine, and lamb, they found that limiting salt intake was good for the brain, especially for those at risk for Alzheimer’s disease. Discussing the field of nutritional research, his prior work studying diet and brain health, and how these findings impact other recommended diets, Willette provides insight into how our current diets can impact our health and cognitive abilities later in life, allowing us to make better choices for the future.

Guest: Auriel Willette, PhD, associate professor of food science and human nutrition, Iowa State University

Better Now than Never: Quit Smoking to Reduce Your Risk for Alzheimer’s Disease

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Researchers have produced many studies on how smoking affects parts of the body, such as the lungs or heart, but what about the brain? In today’s podcast, Adrienne Johnson, PhD, discusses her research on cigarette smoking and risk for dementia and Alzheimer’s disease. As part of a 2021 study, she found a person’s risk for dementia and Alzheimer’s disease can be affected by how recently they’ve smoked. Diving into her research, the effects of smoking on different communities, and resources to support current smokers as they quit, Dr. Johnson details the impact of smoking on the brain and her hopes to develop new interventions to motivate smokers to quit for good.

Guest: Adrienne Johnson, PhD, assistant scientist at the University of Wisconsin Center for Tobacco Research and Intervention

Dentistry and Dementia: The Importance of Caring for Oral Health

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Elisa Ghezzi, DDS, PhD, joins the podcast to discuss the importance of maintaining oral health throughout one’s life, and especially as one grows older. Discussing the effects of oral health on our systemic health, oral health’s connection to dysphagia, and how caregivers can help dementia patients care for their teeth, Dr. Ghezzi provides insight on how vital it is to care for our oral health as we age.

Guest: Elisa Ghezzi, DDS, PhD, adjunct clinical assistant professor, University of Michigan School of Dentistry, provider, Voiage Portable Dentistry

How to Shape Your Brain Health and Reduce Your Risk for Alzheimer’s Disease

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Neuropsychologist and author Michelle Braun, PhD, joins the podcast to talk about lifestyle changes that can support brain health. “We have the ability to make our brain younger than our chronological age,” she says. Braun shares how and details strategies from her new book, High-Octane Brain: 5 Science-Based Steps to Sharpen Your Memory and Reduce Your Risk of Alzheimer’s. Hear about common misconceptions around aging, three possible brain health trajectories, and how to maximize your brain health.

Guest: Michelle Braun, PhD, neuropsychologist and national leader in the field of brain health

Intermittent Fasting and Its Effects on the Brain

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As intermittent fasting has risen in popularity over the last decade, researchers have been exploring its long-term effects on physical health. Dr. Mark Mattson joins to discuss his research on metabolic switching, caloric restrictions, and the cognitive benefits from intermittent fasting. 

Guest: Mark P. Mattson, PhD, Johns Hopkins University School of Medicine, Department of Neurology

Note: It is best to talk with your healthcare provider before engaging in intermittent fasting.

Research Update: Aerobic Exercise and Brain Health

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Aerobic exercise is often a recommendation for maintaining cognitive well-being, however its true connections to brain health are still being investigated to learn its effects on Alzheimer’s disease. Wisconsin ADRC exercise physiologist and researcher Max Gaitán joins the podcast to discuss the recent pilot study “Protocol of Aerobic Exercise and Cognitive Health (REACH)” and the study’s future research into the impact of aerobic exercise on brain health.

Guest: Max Gaitán, MEd, Research Specialist, University of Wisconsin School of Medicine and Public Health Department of Medicine

Building the Brain: Finding the Cognitive Benefits of Physical Activity

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To many people, exercise can seem like an uncertain and intimidating new world. The confusing marketing around it can make it hard to find a healthy, sustainable exercise plan. But it’s important for people to fit movement into their lives because a growing body of research is showing the positive effects that physical activity can have on your brain. Our guests Sarah Lose and Max Gaitan, research specialists and exercise physiologists, discuss building cognitive resilience, defining physical activity, and researching exercise and its links with brain health.

Guests: Sarah Lose, Max Gaitan, Research Specialists and Exercise Physiologists, Okonkwo Lab, Alzheimer’s Disease Research Center, University of Wisconsin-Madison

Finding the Link Between High Blood Pressure and Dementia

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Preventive cardiologist Dr. Heather Johnson joins us this week to discuss how keeping a healthy cardiovascular system can reduce chances of developing dementia. She also discusses her MyHEART study, which aims to help young adults live heart-healthy lives.

Guest: Dr. Heather Johnson, cardiologist with special interest in preventive cardiology, University of Wisconsin School of Medicine and Public Health

The Link Between Neighborhood Disadvantage and Health Outcomes

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Social determinants of health play a big role in our overall well-being. Unfortunately, too often we fail to recognize the impacts that these factors have on our brains and overall health. Dr. Amy Kind and her research team at the University of Wisconsin developed a tool called the Neighborhood Atlas to visualize neighborhood disparities and help facilitate change.

Guest: Dr. Amy Kind, MD, PhD, Associate Professor of Geriatrics, University of Wisconsin School of Medicine and Public Health, Director, VA Dementia Care Clinic, Investigator, Wisconsin ADRC

Connecting the Gut Microbiome to Alzheimer’s Disease

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Examining the bacteria that live in our guts and the role it plays in health is an exciting frontier in scientific inquiry. Researchers are now looking at the gut microbiome for answers about Alzheimer’s disease.

Guest: Nick Vogt, MD/PhD Student, Wisconsin School of Medicine and Public Health, Research Investigator, Wisconsin Alzheimer’s Disease Research Center